ICSI Treatment in Indore

What is ICSI?

Intracytoplasmic sperm injection (ICSI) is a special form of in vitro fertilization (IVF) used to treat male infertility by injecting a single sperm directly into an egg, which is then transferred to the woman’s uterus.

When is ICSI recommended?

ICSI is generally recommended for couples with poor or no fertilization during IVF and for couples where the man has:

1. Very few sperm: Low Sperm quantity in Man this is the main root cause for ICSI treatment need. The male partner’s sperm is collected from the testicles, but ejaculation is not possible due to various factors such as spinal cord injuries, diabetes, or unsuccessful vasectomy reversals, resulting in low sperm count or poor quality.
2. Most abnormal sperm movement. Sperm quality can decrease due to various factors, including spinal cord injuries and diabetes. In the Episode, a vasectomy was performed, and sperm was collected from the testicles, despite the male partner’s inability to ejaculate.
3. Part: Failure of vas deferens recanalization may result in very low sperm count or poor sperm quality. Section

How does the ICSI process work?

ICSI is a part of IVF. Since ICSI is done in a laboratory, your IVF treatment – ICSI will not be much different from IVF treatment without ICSI. However, the “how” of sperm extraction will be different for the male partner.

• For Female

For female couples, the steps are similar to the in vitro fertilization process.

• For Male

In vitro fertilization treatment involves a male partner providing sperm samples on egg birthday, examined under a microscope, and if minimal live sperm exists, extraction may be necessary using procedures like Percutaneous epididymis sperm aspiration (PESA) or testicular sperm extraction (TESE)

Embryologist injects sperm into eggs using a microscope and needle, ensuring all are retrieved, but not guaranteeing fertility. One to three best embryos are transferred to the uterus.

What are the advantages of ICSI?

ICSI offers a higher fertilization rate than IVF, allowing for more embryos and increased cryopreservation. It provides couples with no other options, sperm can be given and can help with unexplained infertility.

What are the risks or side effects?

ICSI, a more invasive procedure, has fewer risks and side effects than IVF, and thousands of children have been born through it, with no evidence of a different birth rate.

IVF/ICSI Cycle Routine

In vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) is a fertility procedure that involves an initial consultation with a specialist, diagnostic tests, and a series of stages. These stages include ovarian stimulation, egg retrieval, sperm collection and preparation, fertilization, embryo culture, embryo selection, embryo transfer, luteal phase support, pregnancy tests, pregnancy monitoring, and cryopreservation. The couple’s medical history, previous fertility treatments, and diagnostic tests are reviewed. The resulting embryos are carefully monitored for quality and development.

ICSI step-by-step procedure

The ICSI procedure involves ovarian stimulation, egg retrieval, sperm collection, egg preparation, and embryo transfer.

1. The woman takes fertility medications to stimulate the ovaries to produce multiple eggs, which are then monitored through blood tests and ultrasound.
2. Once the eggs are mature, a minor surgical procedure called transvaginal oocyte retrieval (TVOR) is performed, which collects the eggs in a sterile container.
3. A sperm sample is collected from the male partner or a sperm donor, and the sperm is processed and prepared for ICSI. The retrieved eggs are examined under a microscope to assess their maturity and quality.
4. A skilled embryologist performs the ICSI procedure, injecting a single sperm directly into the cytoplasm of a mature egg.
5. The fertilized eggs are placed in a controlled incubator to encourage fertilization and early embryo development.
6. Embryos are cultured in the laboratory for several days to reach the blastocyst stage before being transferred into the uterus.
7. The embryologist assesses the quality and development of the embryos and selects the healthiest ones for transfer.
8. Excess embryos can be cryopreserved for future use.
9. Embryos are gently transferred into the woman’s uterus, with the number of embryos varying based on the woman’s age and embryo quality.
10. Pregnancy support may be prescribed to support the early stages of pregnancy.
11. A pregnancy test is performed approximately 10-14 days after the transfer, and regular monitoring through ultrasounds and blood tests is continued to track the pregnancy’s progress.

Examinations and Treatments

The In Vitro Sperm Injection (ICSI) process involves several examinations and treatments. The first step involves a consultation with a fertility specialist to understand the underlying causes of infertility. Diagnostic tests assess factors like ovarian reserve, sperm quality, and uterine health. Ovarian stimulation is crucial, with medications prescribed to stimulate ovaries.

Egg retrieval is performed using a thin needle, and sperm samples are collected and processed. The ICSI procedure involves injecting a single sperm into a mature egg, which is then cultured and transferred into the woman’s uterus. The number of embryos transferred depends on the woman’s age and quality. Progesterone supplements may be prescribed to support the early stages of pregnancy.

Blood Test:

Blood tests are crucial in the Intracytoplasmic Sperm Injection (ICSI) procedure and in vitro fertilization (IVF) to monitor hormonal levels, assess ovarian response, and confirm pregnancy. These tests include baseline hormonal testing to determine ovarian reserve and guide fertility medication dosage. Regular blood tests are conducted during ovarian stimulation to assess follicle growth and adjust medication doses. A trigger shot, typically human chorionic gonadotropin, is scheduled based on blood tests and ultrasound monitoring.

Ultrasound examination

Ultrasound examinations are crucial in the Intracytoplasmic Sperm Injection (ICSI) process, providing real-time visualization of ovaries, uterus, and follicles. They help fertility specialists monitor ovarian stimulation, egg retrieval, trigger shot timing, egg retrieval guidance, and uterine lining for embryo transfer.

Ultrasound also guides egg retrieval, ensuring accurate placement and increasing implantation chances. After embryo transfer, blood tests for hCG confirm pregnancy.

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